group 2024

Regulation of DNA-Dependent Processes

  • Genomic DNA in both prokaryotes and eukaryotes is compacted to fit into cellular compartments. We are interested in proteins that promote such compaction, because they regulate important DNA-dependent activities such as gene expression and DNA repair.
  • When a bacterial pathogen infects a host, it must thwart host defenses intended to incapacitate the invader. Efficient responses therefore promote virulence and allow the pathogen to colonize the host. We are focusing on bacterial transcription factors that respond to host-derived signals to control expression of virulence genes.


Welcome - Spring 2024

Md Saiful Islam

PhD Student

Publication Alert

Kumar, S., Mashkoor, M., Balamurugan, P. and Grove, A.

Yeast Crf1p is an activator with different roles in regulation of target genes.

Yeast 41, 379-400 ( 2024).