Research

Microfluidic impedance-based diagnostic sensors for blood disorders

Diagnostic Sensor
Our research aims to create next-generation diagnostic devices that harness microfluidic channels and impedance-based sensing for analyzing blood composition and identifying diseases such as sepsis, anemia, coagulation disorders, and zoonotic infections. These devices are designed for point-of-care settings, with the goal of shifting diagnostics from centralized labs to on-site and accessible platforms in veterinary and clinical environments. By leveraging impedance spectroscopy, our sensors provide high-sensitivity detection with minimal blood volume, making them ideal for both human and animal health applications.

 

Electroporation based therapeutics

illustration of cellular electroporation
Our research on microfluidic devices for electroporation aims to revolutionize therapeutic delivery by creating precise, efficient, and scalable platforms for in vivo gene and protein therapy. Electroporation enables targeted delivery of therapeutic agents by using controlled electric pulses to permeabilize cell membranes, allowing for the direct entry of DNA, RNA, or other molecules. In the EDIT Lab, we are engineering advanced microfluidic systems that optimize electroporation at the cellular level, ensuring minimal invasiveness and maximizing therapeutic efficacy. This work has potential applications in gene therapy, immunotherapy, and regenerative medicine, with the goal of providing accessible, customizable treatments for various diseases. By refining microfluidic electroporation, we aim to expand the possibilities of cellular therapy, enabling new breakthroughs in precision medicine.